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Molfinity

FLT3-IN-14 - CAS 2620551-45-1

FLT3-IN-14 - CAS 2620551-45-1

MF-0038781-01

$1,383.80 USD
$1,383.80 USD
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Product Details

  • Bioactivity

    FLT3-IN-14 is a potent inhibitor of FLT3, targeting FLT3-WT (IC50: 5.6 nM) and FLT3-ITD (IC50: 1.4 nM) . It inhibits FLT3 (Y591) phosphorylation, arrests the cell cycle in the G1 phase, and induces apoptosis.

  • Target

    FLT, Apoptosis, Others

  • Related Pathways

    Apoptosis, Others, Angiogenesis, Tyrosine Kinase/Adaptors

  • CAS Number

    2620505

  • Molecular Formula

    C25H24N6O2S

  • Molecular Weight

    472.56

  • SMILES

    N(C(NC=1C=C(C(C)(C)C)ON1)=O)C2=CC=C(C3=CN4C=5C=6C(CCC5SC4=N3)=CNC6)C=C2

  • Storage Temperature

    -20°C

  • Shipping Conditions

    Ice Packs

  • Category

    Small Compound