FLT3-IN-32 TFA - CAS 3047195-49-0

FLT3-IN-32 TFA is a potent FLT3 inhibitor with IC50 values of 2.40 nM and 3.83 nM against FLT3-ITD and FLT3-D835Y, respectively. It effectively inhibits the proliferation/survival of human MV4-11 cells with an IC50 of 0.07 nM. FLT3-IN-32 TFA is applicable in acute myeloid leukemia (AML) research.

FLT

Angiogenesis, Tyrosine Kinase/Adaptors

3047146

C30H30F3N5O7

629.58

O=C(O)C(F)(F)F.O=C(NC1=NOC(=C1)C(C)(C)C)NC=2C=CC=3OC(=CC3C2)C(=O)C4=CC=5C(=CC=C(O)C5CN(C)C)N4

-20°C

Ice Packs

Small Compound