FLT3-IN-33 - CAS 3035801-67-0

FLT3-IN-33 (Compound 7r) is a potent FLT3 inhibitor with an IC50 of 7.82 nM. It exhibits excellent anticancer activity against acute myeloid leukemia (AML) cells, such as MV4-11 and MOLM-13 cells. FLT3-IN-33 significantly induces apoptosis and inhibits the phosphorylation of the FLT3 pathway, making it useful for research in AML and other cancers.

Apoptosis, FLT

Apoptosis, Angiogenesis, Tyrosine Kinase/Adaptors

3035734

C25H36N8O

464.61

N(C=1C(=CN=C(NCCC)N1)C=2NC=3C(N2)=CC=C(C3)N4CCN(C)CC4)[C@@H]5CC[C@@H](O)CC5

-20°C

Ice Packs

Small Compound