FLT3/ITD-IN-2 - CAS 2489446-59-3

FLT3/ITD-IN-2 is a potent inhibitor of FLT3-ITD and is able to act on FLT3D835Y (IC50: 0.3 nM), FLT3 (IC50: 0.4 nM) and FLT3-ITD (IC50: 1.0 nM) .FLT3/ITD-IN-2 effectively inhibits the phosphorylation of FLT3 and is able to effectively inhibit the proliferation of acute myeloid leukemia cells.

Others, FLT

Others, Tyrosine Kinase/Adaptors, Angiogenesis

2489446-59-3

C23H26F3N7O2

489.49

C(NC1=C(C(F)(F)F)C=C(C=C1)N2CCOCC2)(=O)C3=C4N(N=C3)C=CC(N[C@@H]5CCCNC5)=N4

-20°C

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Small Compound