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FLT3/ITD-IN-4 - CAS 2278278-04-7

FLT3/ITD-IN-4 - CAS 2278278-04-7

SKU:MF-0045166-01

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  • Bioactivity

    FLT3/ITD-IN-4 (Compound 16) is a selective inhibitor of FLT3 internal tandem repeat mutations (FLT3-ITD) with an IC50 of 2.3 nM and is applicable for studying acute myeloid leukemia.

  • Target

    FLT, c-RET, MAPK, Others, CDK

  • Related Pathways

    Apoptosis, MAPK, Tyrosine Kinase/Adaptors, Cell Cycle/Checkpoint, Angiogenesis, Others

  • CAS Number

    2278278-04-7

  • Molecular Formula

    C25H22N4O5

  • Molecular Weight

    458.47

  • SMILES

    C(=O)(C1=CC=2C(O1)=CC=C(NC(NC=3C=C(C(C)(C)C)ON3)=O)C2)C=4NC=5C(C4)=CC(O)=CC5

  • Storage Temperature

    -20°C

  • Shipping Conditions

    Ice Packs

  • Category

    Small Compound