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Fluorofenidone - CAS 848353-85-5
Fluorofenidone - CAS 848353-85-5
SKU:MF-0012490-01
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$32.42 USD
Regular price
$19.50 USD
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$32.42 USD
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Product Details
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Bioactivity
Fluorofenidone (AKF-PD) attenuates the progression of renal interstitial fibrosis partly by suppressing NADPH oxidase and extracellular matrix (ECM) deposition via the PI3K/Akt signalling pathway. Fluorofenidone is an analogue of AMR69. Which displays equivalent lower toxicity, antifibrotic activity, and longer half-life.
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Target
Akt, PI3K, Others
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Related Pathways
PI3K/Akt/mTOR signaling, Others, Cytoskeletal Signaling
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CAS Number
848353-85-5
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Purity
0.9987
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Molecular Formula
C12H10FNO
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Molecular Weight
203.21
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SMILES
Cc1ccc(=O)n(c1)-c1cccc(F)c1
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Storage Temperature
-20°C
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Shipping Conditions
Ice Packs
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Category
Small Compound