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Molfinity

Fluorofenidone - CAS 848353-85-5

Fluorofenidone - CAS 848353-85-5

SKU:MF-0012490-01

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  • Bioactivity

    Fluorofenidone (AKF-PD) attenuates the progression of renal interstitial fibrosis partly by suppressing NADPH oxidase and extracellular matrix (ECM) deposition via the PI3K/Akt signalling pathway. Fluorofenidone is an analogue of AMR69. Which displays equivalent lower toxicity, antifibrotic activity, and longer half-life.

  • Target

    Akt, PI3K, Others

  • Related Pathways

    PI3K/Akt/mTOR signaling, Others, Cytoskeletal Signaling

  • CAS Number

    848353-85-5

  • Purity

    0.9987

  • Molecular Formula

    C12H10FNO

  • Molecular Weight

    203.21

  • SMILES

    Cc1ccc(=O)n(c1)-c1cccc(F)c1

  • Storage Temperature

    -20°C

  • Shipping Conditions

    Ice Packs

  • Category

    Small Compound