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Fluorphine - CAS 6440-42-2
Fluorphine - CAS 6440-42-2
SKU:MF-0112425-01
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Product Details
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Bioactivity
Fluorphine, an analog of Brorphine, binds to the μ-opioid receptor (MOR) with a Ki of 12.5 nM. It exhibits GTPγS binding activity with an EC50 of 75 nM and β-arrestin 2 recruitment activity with an EC50 of 377 nM, and it also has respiratory depressive effects.
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Target
Opioid Receptor
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Related Pathways
GPCR/G Protein, Endocrinology/Hormones, Neuroscience
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CAS Number
6396
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Molecular Formula
C20H22FN3O
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Molecular Weight
339.41
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SMILES
O=C1NC=2C=CC=CC2N1C3CCN(CC3)C(C4=CC=C(F)C=C4)C
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Storage Temperature
-20°C
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Shipping Conditions
Ice Packs
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Category
Small Compound