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Molfinity

Fluorphine - CAS 6440-42-2

Fluorphine - CAS 6440-42-2

SKU:MF-0112425-01

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  • Bioactivity

    Fluorphine, an analog of Brorphine, binds to the μ-opioid receptor (MOR) with a Ki of 12.5 nM. It exhibits GTPγS binding activity with an EC50 of 75 nM and β-arrestin 2 recruitment activity with an EC50 of 377 nM, and it also has respiratory depressive effects.

  • Target

    Opioid Receptor

  • Related Pathways

    GPCR/G Protein, Endocrinology/Hormones, Neuroscience

  • CAS Number

    6396

  • Molecular Formula

    C20H22FN3O

  • Molecular Weight

    339.41

  • SMILES

    O=C1NC=2C=CC=CC2N1C3CCN(CC3)C(C4=CC=C(F)C=C4)C

  • Storage Temperature

    -20°C

  • Shipping Conditions

    Ice Packs

  • Category

    Small Compound