Fmoc-11-aminoundecanoic acid - CAS 88574-07-6

Fmoc-11-aminoundecanoic acid can be used as a PROTAC linker in the synthesis of PROTACs and other conjugation applicaitons. Fmoc-11-aminoundecanoic acid is an alkane chian with terminal Fmoc-protected amine and carboxylic acid groups. The Fmoc group can be deprotected under basic condition to obtain the free amine which can be used for further conjugations. The terminal carboxylic acid can react with primary amine groups in the presence of activators (e.g. EDC, or HATU) to form a stable amide bond.

Others, PROTAC Linker

PROTAC, Others

88574-07-6

C26H33NO4

423.54

C(OC(NCCCCCCCCCCC(O)=O)=O)C1C=2C(C=3C1=CC=CC3)=CC=CC2

-20°C

Ice Packs

PROTAC