Fmoc-12-aminododecanoic acid - CAS 128917-74-8

Fmoc-12-aminododecanoic acid is an alkane chian with terminal Fmoc-protected amine and carboxylic acid groups. The compound can be used as a PROTAC linker in the synthesis of PROTACs. The Fmoc group can be deprotected under basic condition to obtain the free amine which can be used for further conjugations. The terminal carboxylic acid can react with primary amine groups in the presence of activators (e.g. EDC, or HATU) to form a stable amide bond.

PROTAC Linker, Others

Others, PROTAC

128835

C27H35NO4

437.57

C(OC(NCCCCCCCCCCCC(O)=O)=O)C1C=2C(C=3C1=CC=CC3)=CC=CC2

-20°C

Ice Packs

PROTAC