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FMP-API-1 - CAS 16523-28-7
FMP-API-1 - CAS 16523-28-7
SKU:MF-0112975-01
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Product Details
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Bioactivity
FMP-API-1 is an inhibitor of the A-kinase anchoring protein (AKAP) -PKA interaction. It binds to the allosteric site of the PKAR subunit, enhancing the activity of PKA and AQP2 in PKA knockout cell lines of the renal cortex collecting duct (mpkCCD cells) . FMP-API-1 holds potential for studying nephrogenic diabetes insipidus (NDI) .
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Target
PKA
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Related Pathways
Tyrosine Kinase/Adaptors
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CAS Number
16488
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Molecular Formula
C13H14N2O2
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Molecular Weight
230.262
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SMILES
OC1=CC=C(C=C1N)CC2=CC=C(O)C(N)=C2
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Storage Temperature
-20°C
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Shipping Conditions
Ice Packs
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Category
Small Compound