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Molfinity

FNIII14 - CAS 206536-96-1

FNIII14 - CAS 206536-96-1

SKU:MF-0127255-01

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  • Bioactivity

    FNIII14 is derived from the 14th type III-like (FN-III) repeat sequence of the fibronectin (FN) molecule. It inhibits cellular adhesion to the extracellular matrix (ECM) by inducing β1-integrin (β1integrin) to shift from an active to an inactive state, blocking integrin-mediated signaling. With its antifibrotic and anticancer properties, FNIII14 is useful for research in metabolic diseases, organ fibrosis, and malignancies.

  • Target

    Integrin

  • Related Pathways

    Cytoskeletal Signaling

  • CAS Number

    206536-96-1

  • Molecular Formula

    C103H163N21O35

  • Molecular Weight

    2255.52

  • SMILES

    C([C@@H](NC([C@@H](NC(CNC([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC([C@H]([C@@H](C)O)N)=O)CCC(O)=O)=O)C)=O)[C@@H](C)O)=O)[C@H](CC)C)=O)[C@@H](C)O)=O)=O)CC(C)C)=O)CCC(O)=O)(=O)N1[C@H](C(NCC(N[C@H](C(N[C@H](C(N[C@@H](CC2=CC=C(O)C=C2)C(N[C@H](C(N[C@H](C(N[C@@H](CC3=CC=C(O)C=C3)C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@@H](CC(C)C)C(O)=O)=O)C)=O)[C@H](CC)C)=O)C(C)C)=O)=O)[C@H](CC)C)=O)[C@@H](C)O)=O)=O)CCC(O)=O)=O)[C@@H](C)O)=O)=O)CCC1

  • Storage Temperature

    -20°C

  • Shipping Conditions

    Ice Packs

  • Category

    Peptide