Molfinity
FNIII14 - CAS 206536-96-1
FNIII14 - CAS 206536-96-1
SKU:MF-0127255-01
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Product Details
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Bioactivity
FNIII14 is derived from the 14th type III-like (FN-III) repeat sequence of the fibronectin (FN) molecule. It inhibits cellular adhesion to the extracellular matrix (ECM) by inducing β1-integrin (β1integrin) to shift from an active to an inactive state, blocking integrin-mediated signaling. With its antifibrotic and anticancer properties, FNIII14 is useful for research in metabolic diseases, organ fibrosis, and malignancies.
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Target
Integrin
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Related Pathways
Cytoskeletal Signaling
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CAS Number
206536-96-1
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Molecular Formula
C103H163N21O35
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Molecular Weight
2255.52
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SMILES
C([C@@H](NC([C@@H](NC(CNC([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC([C@H]([C@@H](C)O)N)=O)CCC(O)=O)=O)C)=O)[C@@H](C)O)=O)[C@H](CC)C)=O)[C@@H](C)O)=O)=O)CC(C)C)=O)CCC(O)=O)(=O)N1[C@H](C(NCC(N[C@H](C(N[C@H](C(N[C@@H](CC2=CC=C(O)C=C2)C(N[C@H](C(N[C@H](C(N[C@@H](CC3=CC=C(O)C=C3)C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@@H](CC(C)C)C(O)=O)=O)C)=O)[C@H](CC)C)=O)C(C)C)=O)=O)[C@H](CC)C)=O)[C@@H](C)O)=O)=O)CCC(O)=O)=O)[C@@H](C)O)=O)=O)CCC1
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Storage Temperature
-20°C
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Shipping Conditions
Ice Packs
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Category
Peptide