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Forasartan - CAS 145216-43-9
Forasartan - CAS 145216-43-9
SKU:MF-0046682-01
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Product Details
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Bioactivity
Forasartan is a non - peptide angiotensin II receptor antagonist with antihypertensive activity. Forasartan and angiotensin II compete to bind AT1 receptor subtypes in vascular smooth muscle, thereby blocking angiotensin II-mediated vasoconstriction, leading to vasodilation. In addition, antagonism against AT1 in the adrenal gland prevents angiotensin II-induced adrenal cortical synthesis and aldosterone secretion stimulation.
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Target
Others
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Related Pathways
Others
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CAS Number
145164
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Molecular Formula
C23H28N8
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Molecular Weight
416.52
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SMILES
N1=NNC(=N1)C=2C=CC=CC2C=3N=CC(=CC3)CN4N=C(N=C4CCCC)CCCC
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Storage Temperature
-20°C
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Shipping Conditions
Ice Packs
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Category
Small Compound