Forvisirvat - CAS 2135638-06-9

Forvisirvat (SP-624) is an orally active, brain-permeable, and selective activator of the silent information regulator protein 6 (SIRT6) . It enhances the deacetylase activity of SIRT6, promotes DNA repair and mitochondrial health, and demonstrates antidepressant effects in animal models. Forvisirvat holds promise for the investigation of major depressive disorder.

Sirtuin

DNA Damage/DNA Repair, Chromatin/Epigenetic

2135638-06-9

C19H17ClN2O6

404.8

O=C1[C@@]2(OC=3C1=C(OC)C=C(C3Cl)C=4OC(C)=NN4)C(OC)=CC(=O)C[C@H]2C

-20°C

Ice Packs

Small Compound