Fosifloxuridine nafalbenamide - CAS 1332837-31-6

Fosifloxuridine nafalbenamide (NUC 3373), a pyrimidine nucleotide analogue, is a Thymidylate synthase inhibitor. NUC-3373 has anticancer activity. NUC-3373 is a ProTide transformation of 5-FU that generates much higher concentrations of FUDR-MP in patients' cells.

DNA/RNA Synthesis

DNA Damage/DNA Repair, Cell Cycle/Checkpoint

1332800

0.9587

C29H29FN3O9P

613.53

O(P(OC[C@H]1O[C@H](C[C@@H]1O)N2C(=O)NC(=O)C(F)=C2)(N[C@H](C(OCC3=CC=CC=C3)=O)C)=O)C=4C5=C(C=CC4)C=CC=C5

-20°C

Ice Packs

Small Compound