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Molfinity

Fosmidomycin - CAS 66508-53-0

Fosmidomycin - CAS 66508-53-0

MF-0121762-01

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Product Details

  • Bioactivity

    Fosmidomycin is an orally administered antibiotic that demonstrates antimalarial properties by inhibiting 1-deoxy-D-xylulose 5-phosphate (DOXP) reductoisomerase. It effectively inhibits the P. falciparum strains 3D7, HB3, Dd2, and A2, with IC 50 values of 150, 71, 170, and 150 ng/mL, respectively. Fosmidomycin works synergistically with Clindamycin and alleviates malaria in a mouse model.

  • Target

    Antibiotic, Parasite

  • Related Pathways

    Microbiology/Virology

  • CAS Number

    66508-53-0

  • Molecular Formula

    C4H10NO5P

  • Molecular Weight

    183.1

  • SMILES

    O=CN(O)CCCP(=O)(O)O

  • Storage Temperature

    -20°C

  • Shipping Conditions

    Ice Packs

  • Category

    Small Compound