FPA-124 - CAS 902779-59-3

FPA-124 is a cell-permeable copper complex that acts as a selective Akt (protein kinase B) inhibitor interacting with the homology (PH) and kinase structural domains of Akt to induce apoptosis. It has the advantage of being highly potent and exhibits dose-dependent growth inhibition in a variety of cancer cell lines.

Akt, Apoptosis

Cytoskeletal Signaling, Apoptosis, PI3K/Akt/mTOR signaling

902717

0.9504

C11H9Cl2CuN3O2S

381.73

O=C1C=2C(OC=C1C=[N]3[Cu+2]([Cl-])([Cl-])[S]=C(N)N3)=CC=CC2

-20°C

Ice Packs

Small Compound