FPT - CAS 2048491-06-9

FPT is a 2-aminotetralin and acts as a potent partial agonist at 5-HT1AR, as well as a full agonist at 5-HT1BR and 5-HT1DR, with EC50 values of 39.3 nM, 1.2 nM, and 0.5 nM, respectively. It is a weak agonist at 5-HT7R. In Fmr1 knockout mice, FPT demonstrates anticonvulsant effects and exhibits anxiolytic and pro-social effects in mouse models.

5-HT Receptor

Neuroscience, GPCR/G Protein

2048491-06-9

C18H20FN

269.36

FC1=C(C2=C3C(C[C@@H](N(C)C)CC3)=CC=C2)C=CC=C1

-20°C

Ice Packs

Small Compound