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Molfinity

FR-181877 - CAS 172936-99-1

FR-181877 - CAS 172936-99-1

SKU:MF-0137928-01

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  • Bioactivity

    FR-181877, a nonprostanoid PGI2 agonist, inhibits ADP-induced aggregation of human platelets with an IC50 value of 0.081 microM and has high oral bioavailability (56%) with a long half-life (4.3 h) in rats.

  • Target

    Prostaglandin Receptor, Others

  • Related Pathways

    Others, Immunology/Inflammation, GPCR/G Protein

  • CAS Number

    172836

  • Molecular Formula

    C30H28N2O4

  • Molecular Weight

    480.55

  • SMILES

    C(C1=NN(C[C@@H]2CC=3C(CC2)=C(OCC(O)=O)C=CC3)C(=O)C=C1)(C4=CC=CC=C4)C5=CC=CC=C5

  • Storage Temperature

    -20°C

  • Shipping Conditions

    Ice Packs

  • Category

    Small Compound