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Molfinity
FR-181877 - CAS 172936-99-1
FR-181877 - CAS 172936-99-1
SKU:MF-0137928-01
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$1,778.67 USD
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$1,778.67 USD
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Product Details
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Bioactivity
FR-181877, a nonprostanoid PGI2 agonist, inhibits ADP-induced aggregation of human platelets with an IC50 value of 0.081 microM and has high oral bioavailability (56%) with a long half-life (4.3 h) in rats.
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Target
Prostaglandin Receptor, Others
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Related Pathways
Others, Immunology/Inflammation, GPCR/G Protein
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CAS Number
172836
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Molecular Formula
C30H28N2O4
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Molecular Weight
480.55
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SMILES
C(C1=NN(C[C@@H]2CC=3C(CC2)=C(OCC(O)=O)C=CC3)C(=O)C=C1)(C4=CC=CC=C4)C5=CC=CC=C5
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Storage Temperature
-20°C
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Shipping Conditions
Ice Packs
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Category
Small Compound