FR901379 - CAS 144371-88-0

FR901379 is an echinocandin-like antifungal lipopeptide.1 It is active against C. albicans, C. krusei, C. tropicalis, C. utilis, A. fumigatus, and A. niger fungi (IC50s = <0.003-1.9 μg/ml) . FR901379 is protective against C. albicans infection in mice (ED50 = 1.1 mg/kg) . It also reduces the number of pulmonary cysts and trophozoites in a mouse model of P. carinii infection.

Others, Antibiotic

Microbiology/Virology, Others

144283

C51H82N8O21S

1175.31

CCCCCCCCCCCCCCCC(=O)N[C@H]1C[C@@H](O)[C@H](O)NC(=O)[C@@H]2[C@@H](O)[C@@H](C)CN2C(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@@H]2C[C@@H](O)CN2C(=O)[C@@H](NC1=O)[C@@H](C)O)[C@H](O)[C@@H](O)c1ccc(O)c(OS(O)(=O)=O)c1)[C@H](O)CC(N)=O

-20°C

Ice Packs

Small Compound