Fraxetin - CAS 574-84-5

Fraxetin (7,8-dihydroxy-6-methoxy coumarin) has dual-antioxidative , hepatoprotective and antihyperglycemic functions, it shows potent protective effects against CCl4 induced oxidative stress and hepatic fibrosis, has a marked inhibitory effect on S.aureus proliferation. It increased the level of Nrf2/ARE, and HO-1, inhibit the formation of ROS, cytochrome c release, activation of caspase-3 and 9, and suppressed the up-regulation of Bax.

Apoptosis, Antibacterial

Microbiology/Virology, Apoptosis

485

0.9976

C10H8O5

208.17

COc1cc2ccc(=O)oc2c(O)c1O

-20°C

Ice Packs

Natural Product