Frovatriptan succinate hydrate - CAS 158930-17-7

Frovatriptan succinate hydrate (Frova) is effective in treating the full spectrum of migraine including the associated symptoms of nausea, vomiting, photophobia, and phonophobia. Frovatriptan succinate hydrate can also be used as in mini-prophylaxis in menstrual migraine. Frovatriptan succinate hydrate is a potent, high affinity, selective and orally active 5-HT1B, HT1D receptor agonist and a moderately potent 5-HT7 receptor agonist, with pKi values of 8.6, 8.4, and 6.7, respectively.

5-HT Receptor

GPCR/G Protein, Neuroscience

158906

0.9995

C18H25N3O6

379.41

O.OC(=O)CCC(O)=O.CN[C@@H]1CCc2[nH]c3ccc(cc3c2C1)C(N)=O

-20°C

Ice Packs

Small Compound