FSH receptor antagonist 1 - CAS 487064-35-7

FSH receptor antagonist 1 (compound 10) is a potent antagonist of the G (s) protein-coupled human follicle-stimulating hormone (FSH) receptor. It exhibits an IC50 value of 28 nM in cell lines expressing the human FSH receptor. This compound significantly inhibits follicle growth and ovulation in in vitro mouse models.

Estrogen Receptor/ERR

Endocrinology/Hormones

487022

C33H32N2O2

488.619

O=C(NC1=CC=C2C(=C1)C(C=3C=CC=CC3)(C)CC(N2C(=O)C)(C)C)C=4C=CC(=CC4)C=5C=CC=CC5

-20°C

Ice Packs

Small Compound