FSLLRY-NH2 - CAS 245329-02-6

Selective PAR2 peptide antagonist. Reverses taxol-induced mechanical allodynia, heat hyperalgesia and PKC activation in ICR mice. Blocks ERK activation and collagen production in isolated cardiac fibroblasts. Also reduces symptoms in a mouse model of dermatophyte-associated itch.

Protease-activated Receptor

GPCR/G Protein

245329-02-6

C39H60N10O8

796.97

[C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC([C@H](CC1=CC=CC=C1)N)=O)CO)=O)CC(C)C)=O)CC(C)C)=O)(C(N[C@@H](CC2=CC=C(O)C=C2)C(N)=O)=O)CCCNC(=N)N

-20°C

Ice Packs

Peptide