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Molfinity

FT671 - CAS 1959551-26-8

FT671 - CAS 1959551-26-8

SKU:MF-0025633-01

Regular price $53.35 USD
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  • Bioactivity

    FT671 is a non-covalent, selective USP7 inhibitor (IC50=52 nM) that binds to the catalytic domain of USP7 (Kd=7.8 μM) . It disrupts the stability of USP7 substrates including MDM2, elevates p53, induces p21, and inhibits tumor growth in mice.

  • Target

    DUB

  • Related Pathways

    DNA Damage/DNA Repair, Ubiquitination, Cell Cycle/Checkpoint

  • CAS Number

    1959517

  • Purity

    0.9976

  • Molecular Formula

    C24H23F4N7O3

  • Molecular Weight

    533.48

  • SMILES

    O=C1C2=C(N(N=C2)C3=CC=C(F)C=C3)N=CN1CC4(O)CCN(C(C[C@@H]([C@H](F)F)N5N=C(F)C=C5)=O)CC4

  • Storage Temperature

    -20°C

  • Shipping Conditions

    Ice Packs

  • Category

    Small Compound