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FTI-2148 diTFA - CAS 817586-01-9
FTI-2148 diTFA - CAS 817586-01-9
SKU:MF-0022343-01
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$2,831.68 USD
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$2,831.68 USD
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Product Details
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Bioactivity
FTI-2148 diTFA, a dual inhibitor targeting both farnesyl transferase (FT-1) and geranylgeranyl transferase-1 (GGT-1), functions as a RAS C-terminal mimetic. It exhibits potent inhibitory capabilities with IC50 values of 1.4 nM for FT-1 and 1.7 μM for GGT-1, respectively.
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Target
Others, Transferase
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Related Pathways
Metabolism, Others
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CAS Number
817586-01-9
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Molecular Formula
C26H29F3N4O5S
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Molecular Weight
566.6
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SMILES
OC(=O)C(F)(F)F.CSCC[C@H](NC(=O)c1ccc(CNCc2cnc[nH]2)cc1-c1ccccc1C)C(O)=O
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Storage Temperature
-20°C
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Shipping Conditions
Ice Packs
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Category
Small Compound