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FTI-2148 diTFA - CAS 817586-01-9

FTI-2148 diTFA - CAS 817586-01-9

SKU:MF-0022343-01

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  • Bioactivity

    FTI-2148 diTFA, a dual inhibitor targeting both farnesyl transferase (FT-1) and geranylgeranyl transferase-1 (GGT-1), functions as a RAS C-terminal mimetic. It exhibits potent inhibitory capabilities with IC50 values of 1.4 nM for FT-1 and 1.7 μM for GGT-1, respectively.

  • Target

    Others, Transferase

  • Related Pathways

    Metabolism, Others

  • CAS Number

    817586-01-9

  • Molecular Formula

    C26H29F3N4O5S

  • Molecular Weight

    566.6

  • SMILES

    OC(=O)C(F)(F)F.CSCC[C@H](NC(=O)c1ccc(CNCc2cnc[nH]2)cc1-c1ccccc1C)C(O)=O

  • Storage Temperature

    -20°C

  • Shipping Conditions

    Ice Packs

  • Category

    Small Compound