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FTI-277 hydrochloride - CAS 180977-34-8

FTI-277 hydrochloride - CAS 180977-34-8

SKU:MF-0016475-01

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  • Bioactivity

    FTI-277 hydrochloride (FTI 277 HCl) is an effective and specific farnesyltransferase (FTase) inhibitor (IC50: 500 pM) ; this selectivity is about 100-fold than the closely related GGTase I.

  • Target

    Ras, Apoptosis, Transferase

  • Related Pathways

    GPCR/G Protein, Metabolism, MAPK, Apoptosis

  • CAS Number

    180935

  • Purity

    0.9819

  • Molecular Formula

    C22H30ClN3O3S2

  • Molecular Weight

    484.07

  • SMILES

    Cl.Cl.COC(=O)C(CCSC)NC(=O)c1ccc(NCC(N)CS)cc1-c1ccccc1

  • Storage Temperature

    -20°C

  • Shipping Conditions

    Ice Packs

  • Category

    Small Compound