FUBP1-IN-2 - CAS 1242862-71-0

FUBP1-IN-2 is a potent inhibitor of far upstream binding protein 1 (FUBP1), effectively disrupting the FUBP1-FUSE interaction in the KH4 domain as demonstrated in a gel shift assay. This compound also exhibits binding affinity to FUBP1 in ChIP assays. Furthermore, FUBP1-IN-2 significantly downregulates c-Myc mRNA and protein levels, upregulates p21 mRNA and protein levels, and depletes intracellular polyamines.

C-Myc, Others

Others, Cell Cycle/Checkpoint

1242791

C26H26ClN3O4

479.96

C(O)(=O)C=1C=C(C=CC1NC(=O)C2=CC=C(OC)C=C2)N3CCN(CC3)C4=C(C)C=CC(Cl)=C4

-20°C

Ice Packs

Small Compound