Fulzerasib - CAS 2641747-54-6

Fulzerasib is an orally active KRAS G12C inhibitor that covalently binds to the cysteine residue on the protein, thereby inhibiting the growth of KRAS G12C mutant tumour cell lines, with an IC50 of 2–20 nM, and can be used to treat KRAS G12C mutant non-small cell lung cancer (NSCLC) .

Kras, Ras

MAPK, GPCR/G Protein

2641687

0.9804

C32H30ClFN6O4

617.07

O=C(C=C)N1CCN2C=3C=4C=C(Cl)C(=NC4N(C(=O)C3N(C(=O)C2C1)C)C=5C(=NC=CC5C)C(C)C)C=6C(F)=CC=CC6O

-20°C

Ice Packs

Small Compound