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Molfinity

FX-11 - CAS 213971-34-7

FX-11 - CAS 213971-34-7

MF-0012140-01

$40.65 USD
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Product Details

  • Bioactivity

    FX-11 (LDHA Inhibitor FX11) is A potent, selective and competitive specific inhibitor of lactate dehydrogenase A (LDHA) with a Ki of 8 μM. FX-11 can activate PKM2 (pyruvate kinase M2) . FX-11 can reduce ATP levels, induce oxidative stress and ROS production, and cause cell death. FX-11 appeared antitumor activity during xenotransplantation of lymphoma and pancreatic cancer.

  • Target

    ROS, Reactive Oxygen Species, Dehydrogenase, Apoptosis

  • Related Pathways

    Metabolism, Apoptosis, Immunology/Inflammation, NF-κB

  • CAS Number

    213971-34-7

  • Purity

    0.9895

  • Molecular Formula

    C22H22O4

  • Molecular Weight

    350.41

  • SMILES

    CCCc1c(O)c(O)c(C(O)=O)c2cc(Cc3ccccc3)c(C)cc12

  • Storage Temperature

    -20°C

  • Shipping Conditions

    Ice Packs

  • Category

    Small Compound