FXIa-IN-9 - CAS 2816108-87-7

FXIa-IN-9 (compound 3f) is a potent, selective inhibitor of FXIa, demonstrating strong binding affinity through hydrogen bond formation (human FXIa Ki: 0.17 nM, rabbit FXIa Ki: 0.5 nM) . It exhibits anticoagulant properties, making it valuable for research into thromboembolic conditions, including atrial fibrillation, stroke, myocardial infarction, deep vein thrombosis, and pulmonary embolism [1].

Others, Factor Xa

Metabolism, Others

2816014

C23H18Cl2F3N9O2

580.35

FC=1C(=C(C=CC1Cl)N2N=NC(Cl)=C2)C3=CN(=O)=C(C(CCOC(F)F)N4C=C(C=N4)C=5N(C)N=NC5)C=C3

-20°C

Ice Packs

Small Compound