FXR agonist 9 - CAS 2982502-32-7

FXR agonist9 (compound 26) is a selective, orally active partial agonist of FXR with an EC50 of 0.09 μM (maximum efficacy of 75.13%) . It ameliorates the pathological features of fatty liver disease in mice induced by HFD and CCl4-related metabolic dysfunction.

FXR

Metabolism

2982463

C28H30N2O5

474.55

O=C(O)C=1C=CC=C(C1)NC(=O)C=2C=CC=CC2NC(=O)CCCOC3=CC=C(C=C3)C(C)(C)C

-20°C

Ice Packs

Small Compound