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FXR/CES2 modulator 1 - CAS 3004676-87-0
FXR/CES2 modulator 1 - CAS 3004676-87-0
SKU:MF-0142686-01
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$1,383.80 USD
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$1,383.80 USD
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Product Details
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Bioactivity
Compound LE-77, known as FXR/CES2 modulator 1, functions as a dual regulator that activates FXR and inhibits CES2. It effectively mitigates the intestinal toxicity of irinotecan.
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Target
FXR
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Related Pathways
Metabolism
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CAS Number
3004589
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Molecular Formula
C27H21Cl2NO5
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Molecular Weight
510.36
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SMILES
O=C(O)COC=1C=CC(=CC1)C2=CC=C(OCC=3C(=NOC3C4CC4)C=5C(Cl)=CC=CC5Cl)C=C2
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Storage Temperature
-20°C
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Shipping Conditions
Ice Packs
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Category
Small Compound