GA 0113 - CAS 200639-61-8

GA 0113 is an effective orally active antagonist of the angiotensin II (Ang II) AT1 receptor. It inhibits the hypertensive response induced by Ang II, with an ID50 of 0.032 mg/kg, and dose-dependently increases plasma renin activity for up to 48 hours.

RAAS

Endocrinology/Hormones

200570

C27H24F3N5O2S

539.57

O=S(=O)(NC=1C=CC=CC1C2=NC=3C=CC(=CC3C=C2)CN4C5=NC(=CC(=C5N=C4CC)C)C)C(F)(F)F

-20°C

Ice Packs

Small Compound