GA32 - CAS 1386811-71-7

GA32 (compound 58r) is a potent androgen receptor (AR) /glucocorticoid receptor (GR) dual inhibitor with IC50 values of 0.13 μM and 0.83 μM for AR and GR, respectively. GA32 inhibits the proliferation of Enzalutamide-resistant, castration-resistant prostate cancer both in vitro and in vivo [1].

Glucocorticoid Receptor, Androgen Receptor

Endocrinology/Hormones

1386811-71-7

C23H19N3O3S

417.48

S(=O)(=O)(N1C=2C(CCC1)=CC=CC2)C3=CC(C(NC4=CC=C(C#N)C=C4)=O)=CC=C3

-20°C

Ice Packs

Small Compound