GABAA receptor agent 2 TFA - CAS 1781880-44-1

GABAA receptor agent 2 TFA is a potent, high-affinity GABAA receptor antagonist with an IC50 of 24 nM [human α1β2γ2GABAA-expressing tsA201 cells] and a Ki of 28 nM [rat GABAA receptor]. GABAA receptor agent 2 TFA has no effect on four human GABA transport proteins [hGAT-1, hBGT-1, hGAT-2, and hGAT-3].

GABA Receptor, Others

Neuroscience, Others, Membrane transporter/Ion channel

1781835

C22H22F3N3O3

433.42

O=C(O)C(F)(F)F.ON1N=CC(=C1C=2C=CC=C(C2)C=3C=CC=CC3)C4CCNCC4

-20°C

Ice Packs

Small Compound