Galegine hydrochloride - CAS 2368870-39-5

Galegine hydrochloride, a guanidine derivative derived from G. officinalis, plays a role in inducing weight loss in mice and has contributed to the development of biguanides, including metformin and phenformin. This compound stimulates AMPK activation in 3T3-L1 adipocytes, L6 myotubes, H4IIE rat hepatoma, and HEK293 human kidney cell lines. Additionally, galegine hydrochloride exhibits antibacterial properties, particularly demonstrating a minimum inhibitory concentration of 4 mg/L against Staphylococcus aureus strains[1][2].

Others, AMPK, Antibacterial

Others, PI3K/Akt/mTOR signaling, Chromatin/Epigenetic, Microbiology/Virology

2368870-39-5

C6H14ClN3

163.65

Cl.CC(C)=CCNC(N)=N

-20°C

Ice Packs

Natural Product