Gallinamide A TFA - CAS 1352920-57-0

Gallinamide A TFA is a peptide that exhibits linear deposition and serves as a potent inhibitor of cathepsin L (CatL) with an IC50 of 17.6 pM. It inhibits SARS-CoV-2 infection by targeting CatL (EC50: 28 nM) and also inhibits Plasmodium falciparum with an IC50 of 50 nM [1] [2].

Cysteine Protease, Parasite, SARS-CoV

Microbiology/Virology, Proteases/Proteasome

1352920-57-0

C33H53F3N4O9

706.79

C(C(O)=O)(F)(F)F.C(/C=C/[C@@H](NC([C@@H](NC([C@@H](OC([C@H]([C@H](CC)C)N(C)C)=O)CC(C)C)=O)CC(C)C)=O)C)(=O)N1[C@@H](C)C(OC)=CC1=O

-20°C

Ice Packs

Natural Product