Gamma-Linolenic acid - CAS 506-26-3

Gamma-Linolenic acid (gamolenic acid), is an unsaturated fatty acid synthesized from linoleic acid (LA) by the enzyme delta-6-desaturase. Research on hepatocellular cell lines has shown γ-Linolenic Acid to have induced reactive oxygen species generation including lipid peroxidation, cell growth inhibition, and heme oxygenase-1 production for antioxidant protection against oxidative stress. Further experiments have noted that γ-Linolenic acid inhibits inflammatory responses through inactivation of NFκB and activator protein-1 by suppressed oxidative stress.

ERK, JNK, NF-κB, Apoptosis, Endogenous Metabolite

Apoptosis, NF-κB, MAPK, Metabolism

477

0.9921

C18H30O2

278.43

CCCCC\C=C/C\C=C/C\C=C/CCCCC(O)=O

-20°C

Ice Packs

Natural Product