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Ganciclovir hydrate - CAS 1359968-33-4
Ganciclovir hydrate - CAS 1359968-33-4
SKU:MF-0140997-01
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Product Details
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Bioactivity
Ganciclovir (BW 759) hydrate is a nucleoside analogue that is an orally active antiviral agent with anti-cytomegalovirus activity. Ganciclovir hydrate is also active against members of the herpes group and some other DNA viruses in vitro. Ganciclovir hydrate inhibits the replication of human herpes viruses (HSV 1 and 2, CMV) and adenovirus serotypes 1, 2, 4, 6, 8, 10, 19, 22 and 28 in vitro. Ganciclovir hydrate also has an IC 50 of 5.2 μM against feline herpesvirus type-1 (FHV-1) and can diffuse into the brain [1] [2] [3].
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Target
HSV, Nucleoside Antimetabolite/Analog, Others, Virus Protease, Antibiotic
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Related Pathways
Microbiology/Virology, Others, Cell Cycle/Checkpoint, DNA Damage/DNA Repair
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CAS Number
1359931
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Molecular Formula
C9H15N5O5
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Molecular Weight
273.249
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SMILES
O.Nc1nc(=O)c2ncn(COC(CO)CO)c2[nH]1
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Storage Temperature
-20°C
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Shipping Conditions
Ice Packs
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Category
Small Compound