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Gandotinib - CAS 1229236-86-5

Gandotinib - CAS 1229236-86-5

MF-0006659-01

$45.13 USD
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Product Details

  • Bioactivity

    LY2784544 (Gandotinib (LY2784544) ) is a potent JAK2 inhibitor (IC50: 3 nM), effective in JAK2V617F (Ki: 0.245 nM) . The selectivity is higher 8- and 20-fold than JAK1 and JAK3.

  • Target

    FGFR, VEGFR, FLT, JAK

  • Related Pathways

    Chromatin/Epigenetic, Tyrosine Kinase/Adaptors, JAK/STAT signaling, Stem Cells, Angiogenesis

  • CAS Number

    1229236-86-5

  • Purity

    0.9986

  • Molecular Formula

    C23H25ClFN7O

  • Molecular Weight

    469.94

  • SMILES

    C(C=1C=2N(C(CC3=C(F)C=C(Cl)C=C3)=C(C)N2)N=C(NC=4C=C(C)NN4)C1)N5CCOCC5

  • Storage Temperature

    -20°C

  • Shipping Conditions

    Ice Packs

  • Category

    Small Compound