Ganoderic acid DM - CAS 173075-45-1

Ganoderic acid DM is an antiandrogenic osteoclastogenesis inhibitor, it especially suppresses the expression of c-Fos and nuclear factor of activated T cells c1 (NFATc1), this suppression leads to the inhibition of dendritic cell-specific transmembrane protein (DC-STAMP) expression and reduces osteoclast fusion.

PARP, Apoptosis, Androgen Receptor, PI3K, CDK

DNA Damage/DNA Repair, Cell Cycle/Checkpoint, PI3K/Akt/mTOR signaling, Chromatin/Epigenetic, Endocrinology/Hormones, Apoptosis

173029

C30H44O4

468.67

[H][C@@]1(CC[C@@]2(C)C3=C(CC[C@]12C)[C@@]1(C)CCC(=O)C(C)(C)[C@]1([H])CC3=O)[C@H](C)CC\C=C(/C)C(O)=O

-20°C

Ice Packs

Natural Product