Ganoderic acid X - CAS 86377-53-9

Ganoderic acid X is a potential Mdm2 inhibitor (K (i) = 16nM) . It is a potential anticancer drug, inhibits topoisomerases and induces apoptosis of cancer cells.

MAPK, JNK, Apoptosis, ERK, Caspase, Mdm2, p53, Topoisomerase

MAPK, DNA Damage/DNA Repair, Proteases/Proteasome, Apoptosis

86315

C32H48O5

512.731

[H][C@@]1(C[C@H](OC(C)=O)[C@@]2(C)C3=CC[C@@]4([H])C(C)(C)[C@H](O)CC[C@]4(C)C3=CC[C@]12C)[C@H](C)CC\C=C(/C)C(O)=O

-20°C

Ice Packs

Natural Product