Ganoderiol F - CAS 114567-47-4

Ganoderiol F has anti-inflammatory, cytotoxic and anti-HIV activity, it inhibits activity of topoisomerases in vitro, and it inhibits human immunodeficiency virus-1 protease with IC (50) values of 20-40 microM. It induced HO-1 expression, activation of the mitogen-activated protein kinase EKR and up-regulation of cyclin-dependent kinase inhibitor p16 and suppressed lipopolysaccharide (LPS) -induced nitric oxide (NO) production.

Autophagy, HIV Protease, Androgen Receptor

Endocrinology/Hormones, Proteases/Proteasome, Autophagy, Microbiology/Virology

114516

C30H46O3

454.68

C[C@]12C=3C([C@]4(C)[C@@](CC3)(C(C)(C)C(=O)CC4)[H])=CC[C@]1(C)[C@@]([C@@H](CCC=C(CO)CO)C)(CC2)[H]

-20°C

Ice Packs

Natural Product