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GAPDH-IN-1 - CAS 252212-58-1

GAPDH-IN-1 - CAS 252212-58-1

MF-0112316-01

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Product Details

  • Bioactivity

    GAPDH-IN-1 (Compound F8) is a GAPDH inhibitor, with an IC50 value of 39.31 μM for GAPDH enzyme activity. It forms a covalent adduct with the aspartic acid in the active site, displacing the enzyme's cofactor NAD+, and simultaneously enhances the reactivity of cysteine-reactive probes with the catalytic cysteine.

  • Target

    Endogenous Metabolite

  • Related Pathways

    Metabolism

  • CAS Number

    252153

  • Molecular Formula

    C20H18N2O5

  • Molecular Weight

    366.37

  • SMILES

    N=1N=C(OC1C=2C=CC=C(OCC3OC3)C2)C=4C=CC=C(OCC5OC5)C4

  • Storage Temperature

    -20°C

  • Shipping Conditions

    Ice Packs

  • Category

    Small Compound