Garcinol - CAS 78824-30-3

Garcinol also inhibits histone acetyltransferases (HATs, IC50= 7 μM) and p300/CPB-associated factor (PCAF, IC50 = 5 μM) . Garcinol has anti-inflammatory and anti-cancer activity. Garcinol, a polyisoprenylated benzophenone harvested from Garcinia indica, exerts anti-cholinesterase properties towards acetyl cholinesterase (AChE) and butyrylcholinesterase (BChE) with IC50s of 0.66 μM and 7.39 μM, respectively.

AChR, Cholinesterase (ChE), Apoptosis, Endogenous Metabolite, Histone Acetyltransferase

Chromatin/Epigenetic, Metabolism, Apoptosis, Neuroscience

78791

0.9859

C38H50O6

602.8

CC(C)=CC[C@@H](C[C@@]12C[C@@H](CC=C(C)C)C(C)(C)[C@@](CC=C(C)C)(C(=O)C(C(=O)c3ccc(O)c(O)c3)=C1O)C2=O)C(C)=C

-20°C

Ice Packs

Natural Product