Garvicin KS, GakA - CAS 2098351-24-5

Garvicin KS (GarKS) is a bacteriocin composed of a 34 amino acid peptide, GakA, and two additional peptides, GakB and GakC. GakA alone has been found to reduce fibroblast viability and proliferation. When combined with GakB, GakA forms an effective duo that exhibits notable peptide stability, antimicrobial potency, and an influence on fibroblast viability and proliferation. Among the Garvicin KS peptides, GakB is the most effective against MSSA, with minimum inhibitory concentration (MIC) values ranked as GakB > GakC > GakA [1].

Antibacterial

Microbiology/Virology

2098322

C161H259N43O39S

3453.11

C([C@H](NC([C@@H](NC([C@@H](NC([C@@H](NC(CNC([C@@H](NC([C@@H](NC([C@H](CC=1C=2C(NC1)=CC=CC2)NC(CNC([C@@H](NC([C@H](CC=3C=4C(NC3)=CC=CC4)NC([C@@H](NC([C@@H](NC(CNC(CNC(CNC([C@@H](NC([C@@H](NC(CNC([C@@H](NC(CNC([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC(CNC([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC(CNC([C@H](CCSC)N)=O)=O)C)=O)[C@H](CC)C)=O)[C@H](CC)C)=O)CCCCN)=O)C)=O)=O)C)=O)CCCCN)=O)[C@H](CC)C)=O)C(C)C)=O)=O)CCCCN)=O)=O)[C@H](C)C)=O)CC(C)C)=O)=O)=O)=O)C)=O)CO)=O)=O)CC(C)C)=O)=O)=O)CC(N)=O)=O)C(C)C)=O)=O)CCC(O)=O)=O)CCCCN)=O)[C@H](CC)C)=O)C(N[C@@H](CCCCN)C(O)=O)=O)C=5C=6C(NC5)=CC=CC6

-20°C

Ice Packs

Peptide