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GB1874 - CAS 1011440-46-2
GB1874 - CAS 1011440-46-2
SKU:MF-0098552-01
Regular price
$307.11 USD
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$307.11 USD
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Product Details
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Bioactivity
GB1874 is an inhibitor of the Wnt pathway targeting β-catenin-TCF4 protein-protein interaction (PPI), affecting proliferation and stemness in Wnt-dependent colorectal cancer (CRC) cells and inhibiting the growth of HCT116 tumour xenografts in vivo.
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Target
Wnt/beta-catenin
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Related Pathways
Cytoskeletal Signaling, Stem Cells
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CAS Number
1011392
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Molecular Formula
C24H27N3O2S
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Molecular Weight
421.56
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SMILES
O=C1CCCC1SC2=NN=C(N2C(C=3C=CC=CC3)C)COC4=CC=C(C=C4)CC
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Storage Temperature
-20°C
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Shipping Conditions
Ice Packs
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Category
Small Compound