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Molfinity

GBR-12935 maleate - CAS 1349767-56-1

GBR-12935 maleate - CAS 1349767-56-1

SKU:MF-0145212-01

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  • Bioactivity

    GBR-12935 is a potent and selective dopamine reuptake inhibitor. It was originally developed in its 3H radiolabelled form for the purpose of mapping the distribution of dopaminergic neurons in the brain by selective labelling of dopamine transporter proteins. This has led to potential clinical uses in the diagnosis of Parkinson's disease, although selective radioligands such as Ioflupane (Â1Â2Â3I) are now available for this application. GBR-12935 is now widely used in animal research into Parkinson's disease and the dopamine pathways in the brain. (Source: http://en.wikipedia.org/wiki/GBR-12935) .

  • Target

    Others, Dopamine Receptor

  • Related Pathways

    Neuroscience, GPCR/G Protein, Others

  • CAS Number

    1349710

  • Molecular Formula

    C32H38N2O5

  • Molecular Weight

    530.665

  • SMILES

    OC(=O)\C=C/C(O)=O.C(CN1CCN(CCOC(c2ccccc2)c2ccccc2)CC1)Cc1ccccc1

  • Storage Temperature

    -20°C

  • Shipping Conditions

    Ice Packs

  • Category

    Small Compound