Molfinity
GBR-12935 maleate - CAS 1349767-56-1
GBR-12935 maleate - CAS 1349767-56-1
SKU:MF-0145212-01
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Product Details
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Bioactivity
GBR-12935 is a potent and selective dopamine reuptake inhibitor. It was originally developed in its 3H radiolabelled form for the purpose of mapping the distribution of dopaminergic neurons in the brain by selective labelling of dopamine transporter proteins. This has led to potential clinical uses in the diagnosis of Parkinson's disease, although selective radioligands such as Ioflupane (Â1Â2Â3I) are now available for this application. GBR-12935 is now widely used in animal research into Parkinson's disease and the dopamine pathways in the brain. (Source: http://en.wikipedia.org/wiki/GBR-12935) .
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Target
Others, Dopamine Receptor
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Related Pathways
Neuroscience, GPCR/G Protein, Others
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CAS Number
1349710
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Molecular Formula
C32H38N2O5
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Molecular Weight
530.665
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SMILES
OC(=O)\C=C/C(O)=O.C(CN1CCN(CCOC(c2ccccc2)c2ccccc2)CC1)Cc1ccccc1
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Storage Temperature
-20°C
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Shipping Conditions
Ice Packs
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Category
Small Compound