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GCN2-IN-6 - CAS 2183470-09-7

GCN2-IN-6 - CAS 2183470-09-7

MF-0018051-01

$120.06 USD
$120.06 USD
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Product Details

  • Bioactivity

    GCN2-IN-6 is a potent and orally available GCN2 inhibitor confirmed by in-house enzymatic (IC50: 1.8 nM) and cellular assays (IC50: 9.3 nM) . GCN2-IN-6 is also an eIF2α kinase PERK inhibitor with IC50s of 0.26 nM in enzymatic assay and 230 nM in cells respectively.

  • Target

    PERK

  • Related Pathways

    Apoptosis

  • CAS Number

    2183470-09-7

  • Purity

    0.98

  • Molecular Formula

    C19H12Cl2F2N4O3S

  • Molecular Weight

    485.29

  • SMILES

    Nc1ncc(cn1)C#Cc1c(F)ccc(NS(=O)(=O)c2cc(Cl)cc(CO)c2Cl)c1F

  • Storage Temperature

    -20°C

  • Shipping Conditions

    Ice Packs

  • Category

    Small Compound