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GDC-0339 - CAS 1428569-85-0
GDC-0339 - CAS 1428569-85-0
SKU:MF-0032913-01
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Product Details
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Bioactivity
GDC-0339 is discovered as a potential treatment of multiple myeloma. GDC-0339 is an orally bioavailable and well-tolerated inhibitor of the pan-Pim kinase (Kis: 0.03 nM, 0.1 nM, and 0.02 nM for Pim1, Pim2, and Pim3, respectively) .
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Target
Pim
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Related Pathways
Chromatin/Epigenetic, JAK/STAT signaling
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CAS Number
1428484
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Molecular Formula
C20H22F3N7OS
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Molecular Weight
465.5
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SMILES
Cn1ncc(NC(=O)c2nc(sc2N)-c2c(F)cccc2F)c1N1CC[C@@H](N)[C@H](F)CC1
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Storage Temperature
-20°C
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Shipping Conditions
Ice Packs
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Category
Small Compound